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Bioclinic Naturals EstroVantage EM 90 Vegan Capsules
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Canadian Product
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Dairy Free
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Gluten Free
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Vegan
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SoyFree
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Vegetarian
- $43.49 CAD
- $43.49 CAD
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About Bioclinic Naturals EstroVantage EM 90 Vegan Capsules
BioClinic Naturals EstroVantage EM® is a vegetarian estrogen modulator formula with calcium D-glucarate, indole-3-carbinol, botanical extracts, DIM, and rosemary. It contains no dairy, gluten, soy, egg, fish, shellfish, tree nuts, or GMOs.
Benefits
- Lycopene supplementation decrease IGF-1 by 25%.7
- In a 34 patient randomized controlled trial foods enriched with bioactive compounds, including rosemary extract (Rosemarinus officinalis), were found to be a promising8
- Green tea polyphenols inhibit the proliferation of bad cells.em>in vivoandin vitro9
- Silymarin can down-regulate gene products involved in the proliferation of bad cells. (cyclin D1, EGFR, COX-2, TGF-beta, IGF-IR), invasion (MMP-9), angiogenesis (VEGF) and metastasis (adhesion molecules)10
- Curcumin inhibits cell growth by mediating certain signalling cascades including the modulation of the NF-ºB signalling pathway11
- Sulforaphane can inhibit the expression of estrogen receptor alpha (ERalpha) protein in MCF-7 cells, inhibiting proliferation and down-regulating hormone receptor expression12
- Suitable for vegetarians/vegans
Feature Summary
In general, estrogen can be divided into several biochemically distinct hormones: estrone (E1), estradiol (E2), estriol (E3), and 17²-estradiol.1In premenopausal women, estrogen is enzymatically converted to several specific estrogen metabolites including 2-hydroxyestrone (2-OHE1), 2-hydroxyestradiol (2-OHE2), 4-hydroxyestrone (4-OHE1), 4-hydroxyestradiol (4-OHE2) and 16-hydroxyestrone (16-OHE1). Both 16-OHE1 and 2-OHE have contrasting biological activities at the cellular level with 16-OHE1 being an estrogen agonist and proliferative, while 2-OHE is an estrogen antagonist and antiproliferative.2As such, an increased ratio 2-OHE:16-OHE1 is associated with a reduced risk in premenopausal women.3Several natural products found in EstroVantage EM support this latter concept including DIM, and indole 3 carbinol (I3C). A human study has confirmed that daily supplementation with 300 mg of I3C daily for 12 weeks significantly increased the 2-OH-estrone: estriol metabolite ratio without notable adverse events.4Other compounds in EstroVantage EM, including calcium-d-glucarate, inhibit beta-glucoronidase activity, allowing for the excretion of estrogen before reabsorption.5It is estimated that a 4% calcium glucarate supplemented diet inhibits beta-glucuronidase activity by 70%.6
Bioclinic Naturals EstroVantage EM 90 Vegan Capsules
| Ingredient | Amount |
|---|---|
| Calcium D-Glucarate (d-glucaric acid calcium salt) | 225 mg |
| Indole-3-Carbinol (3-hydroxymethylindole) (Brassica oleracea var. italica) (aerial) | 225 mg |
| Green Tea Extract (Camellia sinensis) (leaf) (80% catechins, 45% EGCG, <1% caffeine) | 150 mg |
| Tomato Extract (Lycopersicon esculentum) (fruit) (5% lycopene) | 150 mg |
| Broccoli Powder (Brassica oleracea var. italica) (aerial) (0.36% sulforaphane) | 82.5 mg |
| Turmeric Extract (Curcuma longa) (root) (95% curcuminoids) | 75 mg |
| Milk Thistle Extract (Silybum marianum) (seed) (60% silymarin) | 75 mg |
| DIM (3,3’-diindolylmethane) | 75 mg |
| Rosemary Extract (Rosmarinus officinalis) (leaf) | 37.5 mg |
** Daily Value not established.
Non-medicinal ingredients: Microcrystalline cellulose, vegetarian capsule (carbohydrate gum [cellulose], purified water), magnesium stearate (vegetable grade), silica.
Bioclinic Naturals EstroVantage EM 90 Vegan Capsules
3 capsule per day taken with food or as directed by a health care professional. Consult a health care professional for use beyond 12 weeks.
Bioclinic Naturals EstroVantage EM 90 Vegan Capsules
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